After three years of protracted diplomacy, the intergovernmental negotiating body of the World Health Organization (WHO) reached consensus on a new international legal instrument on pandemic prevention, preparedness, and response—a powerful international commitment to global health. The Pandemic Agreement was adopted by WHO member states at the World Health Assembly on 20 May 2025.1This global health law reform is a significant multilateral success at a moment of international division, offering structured pathways to guide pandemic preparedness and response. The agreement’s framework for action was designed to practically foster solidarity among nations and includes obligations to adopt non-siloed approaches in pandemic responses, protect the health workforce during pandemics, and strengthen medical supply chains.2The Pandemic Agreement provides an opportunity to break the “panic-neglect” cycle: panicked responses during global health emergencies followed by neglect for preparedness between emergencies. Yet, because upholding global health law is dependent on government commitment and action, the success…